1. His life is marked by vicissitudes.
    他的一生几经沉浮。

2. The vicissitudes of life may suddenly make a rich man very poor.
    在人世的沧桑中，一个有钱人突然也会变成穷光蛋。

1. 变化：viciousness 恶意 | vicissitude 变化 | vicissitudinary 交替的

2. vicissitude的近义词

2. 变迁：异国情调的 exotic | 变迁 vicissitude | 安静的 tranquil

3. vicissitude的意思

3. 盛衰：vicissitude 荣枯 | vicissitude 盛衰 | vicissitudinous 有变化的

4. 荣枯：viciouscircle 恶性循环 | vicissitude 荣枯 | vicissitude 盛衰

1. mutability in life or nature (especially successive alternation from one condition to another)

2. a variation in circumstances or fortune at different times in your life or in the development of something

    e.g. the project was subject to the usual vicissitudes of exploratory research