1. This report describes a rare case of a concurrent epithelioid trophoblastic tumor and a teratoma in a para-aortic lymph node from a 39-year-old male patient with the initial diagnosis of testicular malignant mixed germ-cell tumor. The metastatic lesion was excised 2 years after orchiectomy and chemotherapy.
本文报道一名曾被确诊为睾丸恶性混合性生殖细胞肿瘤的39岁男性，在睾丸切除及化疗后两年出现主动脉旁淋巴结转移，转移灶中居然同时出现上皮样滋养层细胞肿瘤及畸胎瘤成分，这种情况实属罕见。
2. There was no evidence of hepatotoxicity, renal toxicity and myelotoxicity in nude mice bearing human breast cancer given 〓I-EGF over a 4-wk observation period. Conclusions EGFR plays a crucial role in neoplastic infiltration, cell proliferation, lymph node metastasis and may be a significant prognostic factor for long-term survival in breast cancer. By quantitative determining the EGFR, DNA content and morphometric parameters, groups of node-negative cancer patients of high risk could be better identified for more effective clinical management. The complexes of radionuclide-iodine labelled EGF is a promising novel radiopharmaceutical agent for the imaging and radiotherapy of breast cancer in the future.
EGFR异常活化可能在乳腺肿瘤浸润、增殖及转移中起重要作用，EGFR的高表达与乳腺肿瘤的恶性潜能密切相关；EGFR表达结合细胞核形态计量参数及DNA含量进行综合分析对腋淋巴结阴性乳腺癌的预后判断具有重要的参考价值；放射性碘标EGF可通过受体介导，被乳腺癌细胞特异摄取并定位于肿瘤部位而发挥显像及低毒高效的杀肿瘤效应，表明了EGFR核素显像诊断和靶向治疗乳腺癌的可行性和有效性。
3. CD30 positive Th2 lymph cells can promote two kinds immunity reaction by secrete IL-2 and so on, so the CD30 level can comprehansive reflect the recipients immunity state. The sCD30 molecule, a member of the tumor necrosis factor/nerve growth factor receptor superfamily was originally identifed as a cell surface antigen on Hodgkin''s and Reed Sternberg cells and is preferentially expressed on human CD4+ and CD8+T cells that secrete Th2-type cytokines. No or low CD30 expression was found on Th1-type cytokine-secreting T cells. A soluble form of CD30(sCD30) is released into the bloodstream after activation of CD30+T cells. In diseases such as multiple sclerosis in which Th1-type immune responsese predominate, elevated sCD30 serum levels correlated with disease remission, In diseases in which Th2-type immune responses predominate, such as lupus erythematosus or atopic dermatitis, elevated serum sCD30 was associated with increased disease activity. Furthermore, increased serum sCD30 in the early stages of HIV infection predicted a rapid progress in acquired immunodeficiency syndrome.
Mosmann等于1986年根据产生的细胞因子及其生物学功能的不同，将鼠的辅助性T细胞(helper T cell，Th)分为Th1细胞和Th2细胞，Th1细胞通过分泌干扰素—γ(interferon-γ，IFN-γ)、白细胞介素2(Interleukin 2，IL-2)和肿瘤坏死因子-β(tumor necrosis factorβ，TNF-β)促进细胞免疫，Th2细胞通过分泌IL-4、IL-5、IL-6、IL-10、IL-13促进体液免疫。1991年Maggi等证实人的Th细胞同样划分为Th1细胞和Th2细胞，不同的是人Th1细胞和Th2细胞都可以产生IL-2；激活后的Th1细胞和Th2细胞分别表达不同的膜表面抗原，Th1细胞高表达淋巴细胞激活基因-3(LAG-3)及其编码蛋白，Th2细胞高表达CD30抗原，因此CD30抗原表达水平可反映Th2细胞的激活状态及其对免疫功能促进作用。
4. lymph cell
4. The expression of HIF-1α was associated with tumor cell proliferation, lymph node metastasis, estrogen receptor status (P.01). Conclusion ion The expression of HIF-1α increased in breast cancer and it is associated with tumor cell proliferation, lymph node metastasis, estrogen receptor status. Thus, HIF-1α may play an important role in the tumor cell proliferation, vasiformation, progression and metastasis of breast cancer, and may become a new target for tumor treatment.
HIF-1α在乳腺癌组织中的表达明显上调，与肿瘤细胞增殖、血管形成、淋巴结转移、雌激素受体状态相关，提示HIF-1α对乳腺癌的肿瘤细胞增殖、血管形成、生长和侵袭、转移起重要作用，有望成为肿瘤治疗的新靶点。
5. Lymph-vascular space involvement of endometrial cancer cell was observed to be statically significant in the CD44-negative group as opposed to the positive group.
黏附分子CD44在子宫内膜癌发生发展中起一定作用，CD44表达下降与子宫内膜癌细胞通过淋巴脉管间隙转移有关，这些基因表达降低与子宫内膜癌患者不良预后因素有关，有可能作为子宫内膜癌患者的预后指标。
6. Microscopically, ① hyperplastic follicles and plentiful plasma cell and lymphocyte infiltration dispersed in paracortical area as well as the peripheral tissues of the capsule; ② endothelial cells proliferated in the vessels with increased thickness of the wall and infiltration of plasma cells; ③ perivascular inflammation; ④ epithelioid histocytes proliferated with granulomatous changes and multinucleated giant cells; ⑤ conspicuous productive perilymphadenitis and thick capsule of the lymph node were found with fibrosis, accompanied by infiltration of chronic inflammatory cells, mostly plasma cells; ⑥ scattered small dots of necrosis were noted in one ease.
组织病理主要基本病变是：①淋巴滤泡增生，滤泡间和副皮质区血管周围有大量淋巴细胞与浆细胞浸润；②血管闭塞性内膜炎，内皮细胞增生肿胀，管壁增厚并浆细胞浸润，管腔狭窄；③血管周围炎；④上皮样组织细胞增生伴有肉芽肿改变，可见多核巨细胞；⑤被膜及淋巴结周围组织以浆细胞为主的慢性炎细胞浸润和纤维化，导致被膜显著增厚；⑥散在小灶性坏死。
7. Results The occurrence of aggressive NK cell leukemia was found to be higher in Asian. Most of its patients were young. The clinical features were found to be high fever and sweat involving the liver, spleen and lymph nodes and bone marrow, hypohepatia, reactive hemophagocytic syndrome, and hypocytosis, etc. Immunophenotype expressed CD2, CD7, CD16 and CD56. The prognosis of patients was very poor with a survival time of several weeks.
结果 侵袭性NK细胞白血病多见于亚洲人；发病年龄相对较轻；临床常表现为高热、盗汗、肝脾淋巴结骨髓受侵犯、肝功能不全、反应性噬血细胞综合征、血细胞减少等多系统受累，免疫表型表达CD2、CD7、CD16、CD56，预后差，生存时间多以周来计算。
8. Of the tumor. The expressional intensity of PTEN protein in lymph node metastasis positive samples is marked lower than that of it in lymph node metastasis negative samples. There was high correlation between the expressional intensity of PTEN protein and lymph node metastasis (P.05). Conclusions: In this study, the presence of LOH and MSI on 10q23 are not significantly associated with the tumor TNM stage and lymph node metastasis of oesophageal carcinomas. However, other tumor suppressor genes at 10q23 may be involved in the carcinogenesis of human oesophageal squamous cell carcinoma in Chinese population. Mutations of PTEN gene do not play a major role in the carcinogenesis of oesophageal squamous cell carcinoma. There is no statistically significant correlation between the expressional intensity of PTEN protein inoesophageal squamous cell carcinoma and the TNM stage of the tumor, but is associated with the lymph node metastasis. PTEN expression is marked down-regulated in the tumor tissue of the oesophageal squamous cell carcinoma patient with lymph node metastasis. Thus, the lower expressional level of PTEN protein may be a significant risk factor for lymph node metastasis in oesophageal squamous cell carcinoma patients.
有淋巴结转移的食管癌组织中PTEN蛋白质的表达强度明硕士学位论文摘要显低于无淋巴结转移的食髓组织，经 X`检验证实两组间 PTEN蛋白质表达强度呈现显著性差异oo.05人结论：本研究表明：10q23的杂合性缺夫和微卫星不稳定性与食管癌的TN`M分期及淋巴结转移表型无明显相关性，但可能累及此区域的其他肿瘤抑制基因；PTEN基因突变在食管癌的发生、发展中不起主要作用；食管癌组织中的PTEN蛋白质的表达强度与TIM分期无相关性，但与淋巴结转移呈显著性相关，在食管癌淋巴结转移的发生、发展过程中呈现PTEN基因表达下调；PTEN蛋白质的表达水平可能作为判断食管癌患者有无淋巴结转移的重要参数之一。
9. The expression of koilocytoid cell without pathological neck lymphonode metastasis shows the possibility of cervical lymph node metastasis.
2健侧淋巴结凹空细胞的检出，说明已有癌转移的潜能。
10. Objective: The prospective investigation of lymph secluding metastasis of T2-4 N0-phase in head-neck squamous cell carcinoma of small sample, and made prepare for constructiving plasmids.
目的：通过检测T2~4 N0头颈部鳞状细胞癌培养的肿瘤细胞及新鲜活检组织中VEGF-A、C及VEGFR-3的表达情况及构建质粒，探讨是否可以通过组织小样本前瞻性研究了解T2~4 N0患者淋巴管受累及局部淋巴转移情况并为制备VEGFR-3抗体作好准备。
11. HIF-1α expression is significantly associated with tumor grade, clinical staging and lymph node metastasis of human oral squamous cell carcinoma.
在恶性肿瘤的发生发展中，维持氧供和氧耗的平衡是一个非常重要的过程。
12. The lymph node T cells from BALB/c mice immunized with OVA were repeatedly stimulated with OVA to establish OVA specific T cell line and T cell clone were obtained using limiting dilution assay. The T cell receptor usage by the T cell line and clones was analyzed with anchor PCR.
我们首先用OVA免疫BALB／c小鼠，取淋巴结细胞在体外用抗原反复刺激，使抗原特异性的T细胞扩增，建立了〓限制的〓OVA特异性T细胞系，通过有限稀释法进行克隆，获得了三株特异性较高的T细胞克隆。
13. lymph cell的近义词
13. Methods S-P immunohistochemical staining was used to detect the expression of VEGF-C and its reˉceptor Flt-4in10neighboring noncancerous tissue and60NSCLC cases of non-small cell lung cancer and32lymph nodes cases with lymph nodes metastasis of non-small cell lung cancer.
采用免疫组化S-P法检测60例NSCLC原发灶组织、10例癌旁组织、32例伴有肺癌转移的淋巴结组织中VEGF-C、Flt-4的表达，并将结果与肺癌的临床病理特征进行分析。
14. Methods S-P immunohistochemical staining was used to detec t the expression of VEGF-C and its reˉceptor Flt-4in10neighboring noncancerous tissue and60NSCLC cases of non-small cell lung cancer and32lymph nodes cases with lymph nodes metastasis of non-small cell lung cancer.
采用免疫组化S-P法检测60例NSCLC原发灶组织、10例癌旁组织、32例伴有肺癌转移的淋巴结组织中VEGF-C、Flt-4的表达，并将结果与肺癌的临床病理特征进行分析。
15. Results Diagnosis of sebaceous carcinoma demanded immunohistochemistry, and rare parotid sebaceous carcinoma was still distinguished with clear cell carcinoma, grume epidermis carcinoma and acinic cell carcinoma in pathology. By Follow-up of the all patients over 5 years, survival rate for 5 years was 71.4%(20/28), primary focus recurrence in 10 cases, in which, neck lymph node metastasis was discovered in 3 cases, and one was performed operation once again. Four cases lost communication; 2cases died of distant metastasis; 2cases died of other diseases.
结果 皮脂腺癌确诊需要免疫组化检测，而罕见的腮腺皮脂腺癌还需和透明细胞癌、黏液表皮样癌和腺泡细胞癌鉴别，全组病例5年以上随访，5年生存率可达71.4%（20/28），5年内原发灶复发10例，其中，3例伴有区域淋巴结转移而再次手术，4例失访；2例死于远处转移；2例死于其他疾病。
16. Objective: To present the clinicopathological features of two cases of Langerhans''cell histiocytosis primarly in lymph nodes.
目的：报告两例以淋巴结首发的Langerhans细胞组织细胞增生症的临床病理表现。
17. By double-antibodies-ELLISA means, the ways that serum of different concentration of RDN act on Con A''s stimulating spleen lymph cell''s excreting IL2 were measured as well.
目的用血清药理学方法研究穿山龙总皂苷对大鼠脾淋巴细胞增殖及其分泌IL2的影响，探讨其可能的作用机理。
18. The serum of 20% and that of 10% of whole saponin of rdn could lower con a''s stimulating spleen lymph cell''s excreting il 2 (p＜0.01, p＜0.05).conclusionthe serum of whole saponin of rdn can lower con a''s stimulating the proliferation and excretion of il 2 of rats''spleen lymph cell.
结果20%和10%穿山龙总皂苷含药血清可抑制con a诱导的脾淋巴细胞增殖（p.01，p.05），20%和10%穿山龙总皂苷含药血清可抑制con a诱导的脾淋巴细胞分泌il 2（p.01，p.05）。结论穿山龙总皂苷含药血清可抑制con a诱导的大鼠脾淋巴细胞增殖及il 2的产生。
19. Its expression correlates with the desmoplasia that accompanies pancreatic cancer, with the metastasis to lymph nodes by humanbreast carcinoma cells and with the invasion of regional vessels in giant cell tumors of bones.
用纯化的抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入MMP-9抗原、生物素化的抗人MMP-9抗体、HRP标记的亲和素，经过彻底洗涤后用底物TMB显色。TMB在过氧化物酶的催化下转化成蓝色，并在酸的作用下转化成最终的黄色。
20. In this study, the results of 99mTc-tetrofosmin SPECT and CT were directly compared with surgical findings for evaluating the lung and mediastinal lymph node lesions in 32 patients with lung masses, among them 16 squamous cell carcinoma, 8 adenocarcinoma, 4 small cell carcinoma, 2 metastatic lung lesions and 2 tuberculoses.
对32例手术病理证实的肺癌和肺结核病人(其中鳞状上皮癌16例，腺癌8例，小细胞肺癌4例，肺转移癌2例，肺结核2例)，进行99mTc-TF SPECT显像和CT检查，将结果直接与手术结果对比，来评价肺和纵膈淋巴结病变。