1. （婚姻、关系或联系的）破裂，终结
    The break-up of a marriage, relationship, or association is the act of it finishing or coming to an end because the people involved decide that it is not working successfully.

    e.g. Since the break-up of his marriage he had not formed any new relationships.
           他婚姻破裂后没有谈新朋友。
    e.g. ...the acrimonious break-up of the meeting''s first session.
           在争吵中结束的第一次会议

2. （组织或国家的）分裂，解体
    The break-up of an organization or a country is the act of it separating or dividing into several parts.

    e.g. ...the break-up of British Rail for privatisation...
           在私有化过程中英国铁路公司的解体
    e.g. At no time did a majority of Czechoslavakia''s citizens support the country''s break-up.
           大多数捷克斯洛伐克公民一直反对国家分裂。