[医]豚鼠，天竺鼠，荷兰猪：同guinea pig
1. 豚鼠：水貂 Mustela vison 30 | 豚鼠 Cavia cobaya 64 | 兔 Oryctolagus cuniculus 44
1. Objective After Intense pulsed light irradiation cavia cobaya skin, to evaluate the histological change of skin with HE stains; to evaluate the collagen fiber change with nitroxanthic acid stains; to quantitative analysis of hydroxyproline content. Confirm mechanism of action for Intense pulsed light on sun-damaged human skin.
目的 用强脉冲光照射豚鼠背部皮肤后，通过HE染色观察皮肤组织学的改变；用苦味酸染色观察皮肤胶原纤维的改变；定量分析豚鼠皮肤羟脯氨酸的含量，观察皮肤胶原蛋白的变化，进一步研究强脉冲光治疗皮肤光老化的作用机制。
2. Cavia cobaya was vaccinated with pVAX1- hsp65 and pVAX1- hsp65-10 recombinant plasmid, moreover, pVAX 1 and supersonic antigen of MAP as control.
以pVAX1-hsp65和pVAX1-hsp65-10免疫豚鼠，同时设pVAX1和副结核分枝杆菌超声抗原对照组。
3. Cavia cobaya
3. Coli BL21(DE3) with the amount of 11.49% through thin layer chromatography scanning analysis. Cavia cobaya was immunized using the purified cytorrhyctes to produce the anti-serum. Through the determination of the optimum working conditions, the sensitivity test, the specificity test, repeatability test and sample simulation test, the indirect ELISA method was established, which is a broad-spectrum, rapid and specific to detect various of food-poisoning Vibrio simultaneously.
融合毒素蛋白包涵体经纯化，免疫豚鼠制备血清抗体，确定间接ELISA的最佳工作条件，并进行敏感性、特异性、重复性及模拟样品检测试验，建立了食物中毒性弧菌广谱、快速、特异的同步免疫学检测方法。
4. The therapeutic effect of radio frequency role on cavia cobaya skin has a certain degree of timeliness which at least maintains three months.
射频作用豚鼠皮肤后疗效有一定的时效性，并至少能维持3个月。
5. The role of radio frequency (RF) to cavia cobaya skin can stimulate the increase of dermal collagen content and the arrangement of collagen fibers were gradually dense. 2.
结论1.射频作用豚鼠皮肤后可刺激真皮胶原含量增加，胶原纤维排列致密紧凑，从而改善皮肤外观。