1. The experiment is performed at the HI-13 Tandem Accelerator Nuclear Physics National Laboratory of China Institute of Atomic Energy. The DNA samples in TE-buffer are irradiated with dose of 10Gy. The number of shorter fragments of linear form DNA irradiated by high-LET ions is largerthan by low-LET ions. It shows that high-LET radiation induces DSBs more.
利用HI-13串列加速器产生的两种能量的重离子~7Li,对DNA溶液和添加自由基清除剂甘露醇的DNA溶液分别进行了辐照,并通过原子力显微镜观察,发现在相同剂量下,DNA样品经过高LET的离子照射后的碎片中短碎片比低LET情况明显增多,说明高LET值的重离子更容易诱发DNA双链断裂。